IL-2-armored peptide-major histocompatibility class I bispecific antibodies redirect antiviral effector memory CD8+ T cells to induce potent anti-cancer cytotoxic activity with limited cytokine release
T cell engagers (TCEs) are becoming an integral class of biological therapeutic owing to their highly potent ability to eradicate cancer cells. Nevertheless, the widespread utility of classical CD3-targeted TCEs has been limited by narrow therapeutic index (TI) linked to systemic CD4+ T cell activat...
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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פורמט: | ספר |
יצא לאור: |
Taylor & Francis Group,
2024-12-01T00:00:00Z.
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גישה מקוונת: | Connect to this object online. |
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Connect to this object online.3rd Floor Main Library
סימן המיקום: |
A1234.567 |
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עותק 1 | זמין |