Determining the Anticancer Activity of Sphingosine Kinase Inhibitors Containing Heteroatoms in Their Tail Structure

• Asıl Yazarlar: Jitendra Shrestha (Yazar), Seong Woong Kim (Yazar), Su-Bin Kim (Yazar), Yoon Sin Oh (Yazar), Sung Hwan Ki (Yazar), Taeho Lee (Yazar), Sang-Bum Kim (Yazar), Taeuk Park (Yazar), Dong Jae Baek (Yazar), Eun-Young Park (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2022-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Sphingosine kinase (SK) enzyme, a central player of sphingolipid rheostat, catalyzes the phosphorylation of sphingosine to the bioactive lipid mediator sphingosine 1 phosphate (S1P), which regulates cancer cell proliferation, migration, differentiation, and angiogenesis through its extracellular fiv...