Induction of histone deacetylases (HDACs) in human abdominal aortic aneurysm: therapeutic potential of HDAC inhibitors

• Main Authors: María Galán (Author), Saray Varona (Author), Mar Orriols (Author), José Antonio Rodríguez (Author), Silvia Aguiló (Author), Jaume Dilmé (Author), Mercedes Camacho (Author), José Martínez-González (Author), Cristina Rodriguez (Author)
• Format: Book
• Published: The Company of Biologists, 2016-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Clinical management of abdominal aortic aneurysm (AAA) is currently limited to elective surgical repair because an effective pharmacotherapy is still awaited. Inhibition of histone deacetylase (HDAC) activity could be a promising therapeutic option in cardiovascular diseases. We aimed to characteris...