Factor analysis of hepcidin on cardiac iron overload and fibrosis among thalassemia major children

• Main Authors: Syarif Rohimi (Author), Bambang Budi Siswanto (Author), Muchtaruddin Mansyur (Author), Djajadiman Gatot (Author), Ina Sutanto (Author), Jacub Pandelaki (Author), Amiliana M. Soesanto (Author), Teddy Ontoseno (Author)
• Format: Book
• Published: SpringerOpen, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Cardiac iron overload is a common cause of death in thalassemia major and is associated with hepcidin, which is primary iron homeostasis. Therapeutics that could increase hepcidin levels or act as hepcidin agonists might help treat the abnormal iron absorption in individuals with...