Glutathione Induces Keap1 S-Glutathionylation and Mitigates Oscillating Glucose-Induced β-Cell Dysfunction by Activating Nrf2

• المؤلفون الرئيسيون: Xiufang Chen (مؤلف), Qian Zhou (مؤلف), Huamin Chen (مؤلف), Juan Bai (مؤلف), Ruike An (مؤلف), Keyi Zhang (مؤلف), Xinyue Zhang (مؤلف), Hui An (مؤلف), Jitai Zhang (مؤلف), Yongyu Wang (مؤلف), Ming Li (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2024-03-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Glutathione (GSH), a robust endogenous antioxidant, actively participates in the modulation of the redox status of cysteine residues in proteins. Previous studies have indicated that GSH can prevent β-cell failure and prediabetes caused by chronic oscillating glucose (OsG) administration. However, t...