The Role of miRNAs in the Regulation of Pancreatic Cancer Stem Cells

• Main Authors: Sabrina Bimonte (Author), Antonio Barbieri (Author), Maddalena Leongito (Author), Giuseppe Palma (Author), Vitale del Vecchio (Author), Michela Falco (Author), Raffaele Palaia (Author), Vittorio Albino (Author), Mauro Piccirillo (Author), Alfonso Amore (Author), Antonella Petrillo (Author), Vincenza Granata (Author), Francesco Izzo (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pancreatic ductal adenocarcinoma is currently one of the deadliest cancers with low overall survival rate. This disease leads to an aggressive local invasion and early metastases and is poorly responsive to treatment with chemotherapy or chemoradiotherapy. Several studies have shown that pancreatic...