Molecular Tuning of IR-786 for Improved Tumor Imaging and Photothermal Therapy

• Autori principali: Wonbong Lim (Autore), Jae Yong Byun (Autore), Gayoung Jo (Autore), Eun Jeong Kim (Autore), Min Ho Park (Autore), Hoon Hyun (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2022-03-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

A tumor-targeted near-infrared (NIR) fluorophore CA800Cl was developed based on commercially available IR-786 by modulating its physicochemical properties. IR-786, a hydrophobic cationic heptamethine cyanine fluorophore, was previously recognized as a mitochondria-targeting NIR agent with excellent...