Detection of apoptosis mechanism on renal cancer cell treated by 16,17-dehydrodeacetyl-5α-oleandrin compound isolated from Nerium indicum Mill. Leaves.

Detection of apoptosis mechanism on renal cancer cell treated by 16,17-dehydrodeacetyl-5α-oleandrin compound isolated from Nerium indicum Mill. Leaves.

The 16,17-dehydrodeacetyl-5α-oleandrin was isolated from an active fraction of Nerium indicum Mill leaves (fam. Apocynaceae). This compound was cytotoxic against various cancer cells, and selective on A498 cells (Renal cancer). However, the apoptosis mechanism was still unknown yet. Therefore, the a...

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Main Authors: Mae S. H. Wahyuningsih (Author), Sofia Mubarika (Author), Ibnu G. Gandjar (Author), Subagus Wahyuono (Author), AWM. Boersma (Author), K. Nooter (Author)
Format: Book
Published: Universitas Gadjah Mada, 2008-10-01T00:00:00Z.
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