Low frequency of BRAF and KRAS mutations in Chinese patients with low-grade serous carcinoma of the ovary

• Main Authors: Yan Xu (Author), Rui Bi (Author), Yaoxing Xiao (Author), Xiaoyu Tu (Author), Ming Li (Author), Anqi Li (Author), Ling Shan (Author), Shuling Zhou (Author), Wentao Yang (Author)
• Format: Book
• Published: BMC, 2017-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Mounting evidence has shown that KRAS and BRAF are somatic mutations associated with low grade serous carcinoma (LGSC) of the ovary. However, the frequency of KRAS or BRAF mutation was variable in literatures, with a frequency of 16-54% for KRAS mutation and 2-33% for BRAF mutati...