Discovery and Characterization of Novel Anti-schistosomal Properties of the Anti-anginal Drug, Perhexiline and Its Impact on Schistosoma mansoni Male and Female Reproductive Systems.

• Main Authors: Alessandra Guidi (Author), Cristiana Lalli (Author), Emerald Perlas (Author), Giulia Bolasco (Author), Martina Nibbio (Author), Edith Monteagudo (Author), Alberto Bresciani (Author), Giovina Ruberti (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Schistosomiasis, one of the world's greatest human neglected tropical diseases, is caused by parasitic trematodes of the genus Schistosoma. A unique feature of schistosome biology is that the induction of sexual maturation as well as the maintenance of the differentiation status of female repro...