Sortilin Fragments Deposit at Senile Plaques in Human Cerebrum

• मुख्य लेखकों: Xia Hu (लेखक), Zhao-Lan Hu (लेखक), Zheng Li (लेखक), Chun-Sheng Ruan (लेखक), Wen-Ying Qiu (लेखक), Aihua Pan (लेखक), Chang-Qi Li (लेखक), Yan Cai (लेखक), Lu Shen (लेखक), Yaping Chu (लेखक), Bei-Sha Tang (लेखक), Huaibin Cai (लेखक), Xin-Fu Zhou (लेखक), Chao Ma (लेखक), Xiao-Xin Yan (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2017-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Genetic variations in the vacuolar protein sorting 10 protein (Vps10p) family have been linked to Alzheimer's disease (AD). Here we demonstrate deposition of fragments from the Vps10p member sortilin at senile plaques (SPs) in aged and AD human cerebrum. Sortilin changes were characterized in p...