The Effect of Pungent and Tingling Compounds from Piper nigrum L. on Background K+ Currents

• Main Authors: Leopoldo R. Beltrán (Author), Corinna Dawid (Author), Madeline Beltrán (Author), Janina Levermann (Author), Sascha Titt (Author), Sini Thomas (Author), Viktoria Pürschel (Author), Miriam Satalik (Author), Günter Gisselmann (Author), Thomas Hofmann (Author), Hanns Hatt (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Black peppercorns (Piper nigrum L.) elicit a pungent and tingling oral impression. Their pungency is partially explained by the agonist activity of some of their active principles, especially piperine, on TRP channels. However, we recently showed that piperine, as well as other pungent compounds, al...