Adolescent kratom exposure affects cognitive behaviours and brain metabolite profiles in Sprague-Dawley rats

• Main Authors: Aiman Nadhirah Zul Aznal (Author), Nurul Aqmar Mohamad Nor Hazalin (Author), Zurina Hassan (Author), Noorul Hamizah Mat (Author), Nelson Jeng-Yeou Chear (Author), Lay Kek Teh (Author), Mohd Zaki Salleh (Author), Farah Wahida Suhaimi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Adolescence is a critical developmental period during which exposure to psychoactive substances like kratom (Mitragyna speciosa) can cause long-lasting deleterious effects. Here, we evaluated the effects of mitragynine, the main alkaloid of kratom, and lyophilised kratom decoction (LKD) on cognitive...