Anti-Angiogenic Effect of Orally Available Pemetrexed for Metronomic Chemotherapy

• Main Authors: Ruby Maharjan (Author), Rudra Pangeni (Author), Saurav Kumar Jha (Author), Jeong Uk Choi (Author), Kwan-Young Chang (Author), Young Kweon Choi (Author), Jin Woo Park (Author), Youngro Byun (Author)
• Format: Book
• Published: MDPI AG, 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Metronomic chemotherapy (MCT) is defined as the frequent administration of low-dose chemotherapeutics, without long drug-free periods, with the exertion of antitumor activity exclusively through anti-angiogenic mechanisms. In this study, we have developed an orally available formulation of pemetrexe...