Selective alterations of neurons and circuits related to early memory loss in Alzheimer's disease

• Main Authors: María eLlorens-Martín (Author), Lidia eBlazquez-Llorca (Author), Ruth eBenavides-Piccione (Author), Alberto eRabano (Author), Felix eHernandez (Author), Jesus eAvila (Author), Javier eDeFelipe (Author)
• Format: Book
• Published: Frontiers Media S.A., 2014-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A progressive loss of episodic memory is a well-known clinical symptom that characterizes Alzheimer's disease (AD). The beginning of this loss of memory has been associated with the very early, pathological accumulation of tau and neuronal degeneration observed in the entorhinal cortex (EC). Ta...