Development and validation of the prediction score for augmented renal clearance in critically Ill Japanese adults

• Main Authors: Ryusei Mikami (Author), Shungo Imai (Author), Mineji Hayakawa (Author), Hitoshi Kashiwagi (Author), Yuki Sato (Author), Shunsuke Nashimoto (Author), Mitsuru Sugawara (Author), Yoh Takekuma (Author)
• Format: Book
• Published: BMC, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Augmented renal clearance (ARC) decreases the therapeutic concentration of drugs excreted by the kidneys in critically ill patients. Several ARC prediction models have been developed and validated; however, their usefulness in Japan has not been comprehensively investigated. Thus...