Model-Informed Precision Dosing of Linezolid in Patients with Drug-Resistant Tuberculosis

• Autores principales: Laurynas Mockeliunas (Autor), Lina Keutzer (Autor), Marieke G. G. Sturkenboom (Autor), Mathieu S. Bolhuis (Autor), Lotte M. G. Hulskotte (Autor), Onno W. Akkerman (Autor), Ulrika S. H. Simonsson (Autor)
• Formato: Libro
• Publicado: MDPI AG, 2022-03-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Linezolid is an efficacious medication for the treatment of drug-resistant tuberculosis but has been associated with serious safety issues that can result in treatment interruption. The objectives of this study were thus to build a population pharmacokinetic model and to use the developed model to e...