Inhibition of Sox2 Expression in the Adult Neural Stem Cell Niche In Vivo by Monocationic-based siRNA Delivery

• Main Authors: Sylvie Remaud (Author), Silvia Alejandra López-Juárez (Author), Anne-Laure B (Author), Patrick Neuberg (Author), Fabrice Stock (Author), Marie-Elise Bonnet (Author), Rym Ghaddab (Author), Marie Stéphanie Clerget-Froidevaux (Author), Jacqueline Pierre-Simons (Author), Patrick Erbacher (Author), Barbara A Demeneix (Author), Ghislaine Morvan-Dubois (Author)
• Format: Book
• Published: Elsevier, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

RNA interference (RNAi) is a major tool for basic and applied investigations. However, obtaining RNAi data that have physiological significance requires investigation of regulations and therapeutic strategies in appropriate in vivo settings. To examine in vivo gene regulation and protein function in...