Nrf2 Plays a Key Role in Erythropoiesis during Aging

• Main Authors: Serge Cedrick Toya Mbiandjeu (Author), Angela Siciliano (Author), Alessandro Mattè (Author), Enrica Federti (Author), Massimiliano Perduca (Author), Davide Melisi (Author), Immacolata Andolfo (Author), Angela Amoresano (Author), Achille Iolascon (Author), Maria Teresa Valenti (Author), Francesco Turrini (Author), Michele Bovi (Author), Arianna Pisani (Author), Antonio Recchiuti (Author), Domenico Mattoscio (Author), Veronica Riccardi (Author), Luca Dalle Carbonare (Author), Carlo Brugnara (Author), Narla Mohandas (Author), Lucia De Franceschi (Author)
• Format: Book
• Published: MDPI AG, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aging is characterized by increased oxidation and reduced efficiency of cytoprotective mechanisms. Nuclear factor erythroid-2-related factor (Nrf2) is a key transcription factor, controlling the expression of multiple antioxidant proteins. Here, we show that Nrf2^−/− mice displ...