In Vitro, Ex Vivo and In Vivo Evaluation of Microcontainers for Oral Delivery of Insulin

• Ngā kaituhi matua: Jacob Rune Jørgensen (Author), Feiyang Yu (Author), Ramakrishnan Venkatasubramanian (Author), Line Hagner Nielsen (Author), Hanne Mørck Nielsen (Author), Anja Boisen (Author), Thomas Rades (Author), Anette Müllertz (Author)
• Hōputu: Pukapuka
• I whakaputaina: MDPI AG, 2020-01-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Enhancing the oral bioavailability of peptides has received a lot of attention for decades but remains challenging, partly due to low intestinal membrane permeability. Combining a permeation enhancer (PE) with unidirectionally releasing microcontainers (MCs) has previously been shown to increase ins...