Effects of 3-Methyladenine on Microglia Autophagy and Neuronal Apoptosis After Radiation-Induced Brain Injury

• Main Authors: Huichao Feng (Author), Yahuan Cui (Author), Jing Liu (Author), Meiyi Liu (Author), Wei Zhou (Author), Zhenyu Yan (Author), Haixia Zhang (Author), Yingman Wang (Author), Xueming Wang (Author), Xiaomin Liu (Author), Naiyao Chen (Author)
• Format: Book
• Published: SAGE Publishing, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective To determine the effect of the autophagy inhibitor, 3-methyladenine (3-MA), on cognitive function changes, microglia activity, neuronal apoptosis, and inflammation in rats following radiation-induced brain injury. Methods The following groups were established: control, model, and 3-MA. A r...