Theoretical design of a new chimeric protein for the treatment of breast cancer

• Main Authors: Meysam Soleimani (Author), Karim Mahnam (Author), Hamid Mirmohammad-Sadeghi (Author), Hojjat Sadeghi-Aliabadi (Author), Ali Jahanian-Najafabadi (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

p28 and NRC peptides are two anticancer peptides with various mechanisms have shown to be effective against breast cancer. Therefore, it seems that construction of a chimeric protein containing the two peptides might cause synergistic cytotoxic effects. However, since the two peptides bear opposite...