Cationic Calix[4]arene Vectors to Efficiently Deliver AntimiRNA Peptide Nucleic Acids (PNAs) and miRNA Mimics

• Main Authors: Jessica Gasparello (Author), Chiara Papi (Author), Matteo Zurlo (Author), Stefano Volpi (Author), Roberto Gambari (Author), Roberto Corradini (Author), Alessandro Casnati (Author), Francesco Sansone (Author), Alessia Finotti (Author)
• Format: Book
• Published: MDPI AG, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

One of the most appealing approaches for regulating gene expression, named the "microRNA therapeutic" method, is based on the regulation of the activity of microRNAs (miRNAs), the intracellular levels of which are dysregulated in many diseases, including cancer. This can be achieved by miR...