Development and validation of a HPLC analytical assay method for efavirenz tablets: a medicine for HIV infections

• Main Authors: Osnir de Sá Viana (Author), Flávia Patrícia Morais Medeiros (Author), Severino Grangeiro-Júnior (Author), Miracy Muniz Albuquerque (Author), Mônica Felts La Roca Soares (Author), José Lamartine Soares-Sobrinho (Author), Lariza Darlene Santos Alves (Author), Larissa Araújo Rolim (Author), Keyla Emanuelle Ramos da Silva (Author), Pedro José Rolim-Neto (Author)
• 格式: 圖書
• 出版: Universidade de São Paulo, 2011-03-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Efavirenz is a reverse transcriptase non analog nucleoside inhibitor used to treat HIV infections. A simple assay method by high performance liquid chromatography was developed and validated for efavirenz tablets. The physical chemical characteristics of efavirenz were investigated to developing the...