Pharmacokinetics of Pullulan-Dexamethasone Conjugates in Retinal Drug Delivery

• Main Authors: Eva Kicková (Author), Amir Sadeghi (Author), Jooseppi Puranen (Author), Shirin Tavakoli (Author), Merve Sen (Author), Veli-Pekka Ranta (Author), Blanca Arango-Gonzalez (Author), Sylvia Bolz (Author), Marius Ueffing (Author), Stefano Salmaso (Author), Paolo Caliceti (Author), Elisa Toropainen (Author), Marika Ruponen (Author), Arto Urtti (Author)
• Format: Book
• Published: MDPI AG, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The treatment of retinal diseases by intravitreal injections requires frequent administration unless drug delivery systems with long retention and controlled release are used. In this work, we focused on pullulan (≈67 kDa) conjugates of dexamethasone as therapeutic systems for intravitreal administr...