White-to-brite conversion in human adipocytes promotes metabolic reprogramming towards fatty acid anabolic and catabolic pathways

• Main Authors: V. Barquissau (Author), D. Beuzelin (Author), D.F. Pisani (Author), G.E. Beranger (Author), A. Mairal (Author), A. Montagner (Author), B. Roussel (Author), G. Tavernier (Author), M.-A. Marques (Author), C. Moro (Author), H. Guillou (Author), E.-Z. Amri (Author), D. Langin (Author)
• Format: Book
• Published: Elsevier, 2016-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Fat depots with thermogenic activity have been identified in humans. In mice, the appearance of thermogenic adipocytes within white adipose depots (so-called brown-in-white i.e., brite or beige adipocytes) protects from obesity and insulin resistance. Brite adipocytes may originate from d...