Interferon-γ regulates immunosuppression in septic mice by promoting the Warburg effect through the PI3K/AKT/mTOR pathway

Abstract Background The main cause of high mortality from sepsis is that immunosuppression leads to life-threatening organ dysfunction, and reversing immunosuppression is key to sepsis treatment. Interferon γ (IFNγ) is a potential therapy for immunosuppression of sepsis, promoting glycolysis to rest...

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Main Authors: Xu-zhe Fu (Author), Yu Wang (Author)
Format: Book
Published: BMC, 2023-07-01T00:00:00Z.
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