Therapeutic uses of topotecan for thoracic malignancies

• Asıl Yazarlar: Saoirse O. Dolly (Yazar), Craig P. Carden (Yazar), James S. Myerson (Yazar), Martina Puglisi (Yazar), Mary E. O'Brien (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2011-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Topotecan, a topoisomerase 1 inhibitor (topo1-i), is a semi-synthetic derivative of camptothecan with wellestablished cytotoxic properties. It is licensed for the treatment of relapsed, sensitive small cell lung cancer (SCLC) and for second line treatment in ovarian cancer. Studies have also shown t...