Mechanical Strain-Mediated Tenogenic Differentiation of Mesenchymal Stromal Cells Is Regulated through Epithelial Sodium Channels

• Main Authors: Hui Yin Nam (Author), Malliga Raman Murali (Author), Raja Elina Ahmad (Author), Belinda Pingguan-Murphy (Author), Hanumantha Rao Balaji Raghavendran (Author), Tunku Kamarul (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

It has been suggested that mechanical strain may elicit cell differentiation in adult somatic cells through activation of epithelial sodium channels (ENaC). However, such phenomenon has not been previously demonstrated in mesenchymal stromal cells (MSCs). The present study was thus conducted to inve...