Improved Radiolytic Stability of a ⁶⁸Ga-labelled Collagelin Analogue for the Imaging of Fibrosis

• Main Authors: Irina Velikyan (Author), Ulrika Rosenström (Author), Maria Rosestedt (Author), Olof Eriksson (Author), Gunnar Antoni (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

There is an unmet medical need for non-invasive, sensitive, and quantitative methods for the assessment of fibrosis. Herein, an improved collagelin analogue labelled with gallium-68 for use with positron emission tomography (PET) is presented. A cyclic peptide, c[CPGRVNleHGLHLGDDEGPC], was synthesiz...