A comparative study of next-generation sequencing and fragment analysis for the detection and allelic ratio determination of FLT3 internal tandem duplication

• 主要な著者: Jin Ju Kim (著者), Kwang Seob Lee (著者), Taek Gyu Lee (著者), Seungjae Lee (著者), Saeam Shin (著者), Seung-Tae Lee (著者)
• フォーマット: 図書
• 出版事項: BMC, 2022-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Abstract Background Currently, FLT3 internal tandem duplication (ITD) is tested by fragment analysis. With next-generation sequencing (NGS), however, not only FLT3 ITD but also other mutations can be detected, which can provide more genetic information on disease. Methods We retrospectively reviewed...