A comparative study of next-generation sequencing and fragment analysis for the detection and allelic ratio determination of FLT3 internal tandem duplication

• Ngā kaituhi matua: Jin Ju Kim (Author), Kwang Seob Lee (Author), Taek Gyu Lee (Author), Seungjae Lee (Author), Saeam Shin (Author), Seung-Tae Lee (Author)
• Hōputu: Pukapuka
• I whakaputaina: BMC, 2022-01-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Abstract Background Currently, FLT3 internal tandem duplication (ITD) is tested by fragment analysis. With next-generation sequencing (NGS), however, not only FLT3 ITD but also other mutations can be detected, which can provide more genetic information on disease. Methods We retrospectively reviewed...