Identification of single nucleotide variants using position-specific error estimation in deep sequencing data

• मुख्य लेखकों: Dimitrios Kleftogiannis (लेखक), Marco Punta (लेखक), Anuradha Jayaram (लेखक), Shahneen Sandhu (लेखक), Stephen Q. Wong (लेखक), Delila Gasi Tandefelt (लेखक), Vincenza Conteduca (लेखक), Daniel Wetterskog (लेखक), Gerhardt Attard (लेखक), Stefano Lise (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2019-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Targeted deep sequencing is a highly effective technology to identify known and novel single nucleotide variants (SNVs) with many applications in translational medicine, disease monitoring and cancer profiling. However, identification of SNVs using deep sequencing data is a chall...