Correlation of TTF-1 immunoexpression and EGFR mutation spectrum in non-small cell lung carcinoma

• Main Authors: Tripti Nakra (Author), Varsha Singh (Author), Aruna Nambirajan (Author), Prabhat Singh Malik (Author), Anant Mohan (Author), Deepali Jain (Author)
• Format: Book
• Published: Korean Society of Pathologists & the Korean Society for Cytopathology, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background Thyroid transcription factor (TTF-1) is a diagnostic marker expressed in 75%-85% of primary lung adenocarcinomas (ACs). Activating mutations in the tyrosine kinase domain of the epidermal growth factor receptor (EGFR) gene is the most common targetable driver alteration in lung AC. Previo...