Reg-2, a downstream signaling protein in the ciliary neurotrophic factor survival pathway, alleviates experimental autoimmune encephalomyelitis

• Main Authors: Hong eJiang (Author), Ke-Wei eTian (Author), Fan eZhang (Author), Beibei eWang (Author), Shu eHan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ciliary neurotrophic factor (CNTF), originally described as a neurocytokine that could support the survival of neurons, has been recently found to alleviate demyelination, prevent axon loss, and improve functional recovery in a rat model of acute experimental autoimmune encephalomyelitis (EAE). Howe...