Expression and purification of truncated diphtheria toxin, DT386, in Escherichia coli: An attempt for production of a new vaccine against diphtheria

• Главные авторы: Fatemeh Shafiee (Автор), Mohammad Rabbani (Автор), Mahdi Behdani (Автор), Ali Jahanian-Najafabadi (Автор)
• Формат: ‌
• Опубликовано: Wolters Kluwer Medknow Publications, 2016-01-01T00:00:00Z.
• Предметы: article
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The aim of this study was to produce a recombinant protein consisting of the catalytic and translocation domains of diphtheria toxin for its later application as a vaccine candidate against Corynebacterium diphtheria. To achieve this goal, at first, the amino acid sequence of DT386 was used for pred...