The Effect of Microbubble-Assisted Ultrasound on Molecular Permeability across Cell Barriers

• Main Authors: Charis Rousou (Author), Josanne de Maar (Author), Boning Qiu (Author), Kim van der Wurff-Jacobs (Author), Marika Ruponen (Author), Arto Urtti (Author), Sabrina Oliveira (Author), Chrit Moonen (Author), Gert Storm (Author), Enrico Mastrobattista (Author), Roel Deckers (Author)
• Format: Book
• Published: MDPI AG, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The combination of ultrasound and microbubbles (USMB) has been applied to enhance drug permeability across tissue barriers. Most studies focused on only one physicochemical aspect (i.e., molecular weight of the delivered molecule). Using an in vitro epithelial (MDCK II) cell barrier, we examined the...