Effect and Mechanism of TL1A Expression on Epithelial-Mesenchymal Transition during Chronic Colitis-Related Intestinal Fibrosis

• Main Authors: Jia Wenxiu (Author), Yang Mingyue (Author), Han Fei (Author), Luo Yuxin (Author), Wu Mengyao (Author), Li Chenyang (Author), Song Jia (Author), Zhang Hong (Author), David Q. Shih (Author), Stephan R. Targan (Author), Zhang Xiaolan (Author)
• Format: Book
• Published: Hindawi Limited, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and Aims. Recent evidences reveal that epithelial to mesenchymal transition (EMT) exacerbates the process of intestinal fibrosis. Tumor necrosis factor-like ligand 1A (TL1A) is a member of the tumor necrosis family (TNF), which can take part in the development of colonic inflammation and...