The flavonoid luteolin reduces mutant huntingtin aggregation and cytotoxicity in huntingtin-mutated neuroblastoma cells

• Главные авторы: Azza Ramadan (Автор), Abuelnor Mohammed (Автор), Asim Ahmed Elnour (Автор), Adel Sadeq (Автор), Nadia Al Mazrouei (Автор), Maisoun Alkaabi (Автор), Khalid Awad Al-Kubaisi (Автор), Semira Abdi Beshir (Автор), Vineetha Menon (Автор), Abdulla AlAmoodi (Автор), Kishore Ganana Sam (Автор), Ali Awadallah Ali Mohamed Saeed (Автор), Sami Fatehi Abdalla (Автор), Samah Mohammed Hussein (Автор)
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• Опубликовано: Elsevier, 2023-12-01T00:00:00Z.
• Предметы: article
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Background: Huntington's disease is an inherited progressive neurodegenerative disorder caused by an expansion of the polyglutamine tract leading to malformation and aggregation of the mutant huntingtin protein in the cell cytoplasm and nucleus of affected brain regions. The development of neur...