The flavonoid luteolin reduces mutant huntingtin aggregation and cytotoxicity in huntingtin-mutated neuroblastoma cells

• Main Authors: Azza Ramadan (Author), Abuelnor Mohammed (Author), Asim Ahmed Elnour (Author), Adel Sadeq (Author), Nadia Al Mazrouei (Author), Maisoun Alkaabi (Author), Khalid Awad Al-Kubaisi (Author), Semira Abdi Beshir (Author), Vineetha Menon (Author), Abdulla AlAmoodi (Author), Kishore Ganana Sam (Author), Ali Awadallah Ali Mohamed Saeed (Author), Sami Fatehi Abdalla (Author), Samah Mohammed Hussein (Author)
• Format: Book
• Published: Elsevier, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Huntington's disease is an inherited progressive neurodegenerative disorder caused by an expansion of the polyglutamine tract leading to malformation and aggregation of the mutant huntingtin protein in the cell cytoplasm and nucleus of affected brain regions. The development of neur...