Metagenomic-based pathogen surveillance for children with severe pneumonia in pediatric intensive care unit

• Main Authors: Meijin Li (Author), Jing Wang (Author), Zhongwei Yao (Author), Hailing Liao (Author), Shufen Su (Author), Xuying Yang (Author), Mingzhou Xie (Author), Yinan Zheng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundPneumonia is a significant cause of morbidity and mortality in children. Metagenomic next-generation sequencing (mNGS) has the potential to assess the landscape of pathogens responsible for severe pulmonary infection.MethodsBronchoalveolar lavage fluid (BALF) samples of 262 children with s...