Combinatory Use of hLF(1-11), a Synthetic Peptide Derived from Human Lactoferrin, and Fluconazole/Amphotericin B against <i>Malassezia furfur</i> Reveals a Synergistic/Additive Antifungal Effect

• Main Authors: Carlo P. J. M. Brouwer (Author), Bart Theelen (Author), Youp van der Linden (Author), Nick Sarink (Author), Mahfuzur Rahman (Author), Saleh Alwasel (Author), Claudia Cafarchia (Author), Mick M. Welling (Author), Teun Boekhout (Author)
• Format: Book
• Published: MDPI AG, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The increasing resistance of <i>Malassezia</i> yeasts against commonly used antifungal drugs dictates the need for novel antifungal compounds. Human lactoferrin-based peptides show a broad spectrum of antimicrobial activities. Various assays were performed to find the optimal...