Insights into the pharmacodynamics and pharmacokinetics of meldonium after exposure to acute high altitude

• Main Authors: Fengying Liu (Author), Xin Sui (Author), Qian Wang (Author), Jinglai Li (Author), Weijie Yang (Author), Yi Yang (Author), Zhenyu Xiao (Author), Yangyang Sun (Author), Xiaoxuan Guo (Author), Xinyi Yang (Author), Jun Yang (Author), Yongan Wang (Author), Yuan Luo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Meldonium, a well-known cardioprotective drug, has been reported to be protective against pulmonary injury at high altitudes; however, the pharmacodynamics of meldonium in other vital organs under acute high-altitude injury are less investigated and the related pharmacokinetics have not b...