The role of SAXS and molecular simulations in 3D structure elucidation of a DNA aptamer against lung cancer
Aptamers are short, single-stranded DNA or RNA oligonucleotide molecules that function as synthetic analogs of antibodies and bind to a target molecule with high specificity. Aptamer affinity entirely depends on its tertiary structure and charge distribution. Therefore, length and structure optimiza...
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Autors principals: | , , , , , , , , , , , , , , , , , , |
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Format: | Llibre |
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Elsevier,
2021-09-01T00:00:00Z.
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Còpia 1 | Disponible |