A Scd1-mediated metabolic alteration participates in liver responses to low-dose bavachin

• Main Authors: Pan Shen (Author), Zhi-Jie Bai (Author), Lei Zhou (Author), Ning-Ning Wang (Author), Zhe-Xin Ni (Author), De-Zhi Sun (Author), Cong-Shu Huang (Author), Yang-Yi Hu (Author), Cheng-Rong Xiao (Author), Wei Zhou (Author), Bo-Li Zhang (Author), Yue Gao (Author)
• Format: Book
• Published: Elsevier, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hepatotoxicity induced by bioactive constituents in traditional Chinese medicines or herbs, such as bavachin (BV) in Fructus Psoraleae, has a prolonged latency to overt drug-induced liver injury in the clinic. Several studies have described BV-induced liver damage and underlying toxicity mechanisms,...