Biological Evaluations and Computer-Aided Approaches of Janus Kinases 2 and 3 Inhibitors for Cancer Treatment: A Review

• Main Authors: Lenci K. Vázquez-Jiménez (Author), Gildardo Rivera (Author), Alfredo Juárez-Saldivar (Author), Jessica L. Ortega-Balleza (Author), Eyra Ortiz-Pérez (Author), Elena Jaime-Sánchez (Author), Alma Paz-González (Author), Edgar E. Lara-Ramírez (Author)
• Format: Book
• Published: MDPI AG, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cancer remains one of the leading diseases of mortality worldwide. Janus kinases 2/3 (JAK2/3) have been considered a drug target for the development of drugs to treat different types of cancer. JAK2/3 play a critical role in innate immunity, inflammation, and hematopoiesis by mediating the signaling...