Therapy targeted to the NLRP3 inflammasome in chronic kidney disease

Background: The NLRP3 inflammasome is a cytoplasmic polymeric protein complex composed of the cytoplasmic sensor NLRP3, the apoptosis-related spot-like protein ASC, and the inflammatory protease caspase-1. NLRP3 activates and releases IL-1β through classical pathways, and IL-18 mediates inflammation...

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Main Authors: Yong Ji (Author), Hu Hua (Author), Zhanjun Jia (Author), Aihua Zhang (Author), Guixia Ding (Author)
Format: Book
Published: Karger Publishers, 2024-05-01T00:00:00Z.
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3rd Floor Main Library

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