Therapy targeted to the NLRP3 inflammasome in chronic kidney disease
Background: The NLRP3 inflammasome is a cytoplasmic polymeric protein complex composed of the cytoplasmic sensor NLRP3, the apoptosis-related spot-like protein ASC, and the inflammatory protease caspase-1. NLRP3 activates and releases IL-1β through classical pathways, and IL-18 mediates inflammation...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
Karger Publishers,
2024-05-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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