Naproxen Based 1,3,4-Oxadiazole Derivatives as EGFR Inhibitors: Design, Synthesis, Anticancer, and Computational Studies

• Päätekijät: Mohammad Mahboob Alam (Tekijä), Syed Nazreen (Tekijä), Abdulraheem S. A. Almalki (Tekijä), Ahmed A. Elhenawy (Tekijä), Nawaf I. Alsenani (Tekijä), Serag Eldin I. Elbehairi (Tekijä), Azizah M. Malebari (Tekijä), Mohammad Y. Alfaifi (Tekijä), Meshari A. Alsharif (Tekijä), Sulaiman Y. M. Alfaifi (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2021-08-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

A library of novel naproxen based 1,3,4-oxadiazole derivatives (<b>8</b>-<b>16</b> and <b>19</b>-<b>26</b>) has been synthesized and screened for cytotoxicity as EGFR inhibitors. Among the synthesized hybrids, compound2-(4-((5-((<i>S</i>)-1...