A Preliminary Investigation of Additive Manufacture to Fabricate Human Nail Plate Surrogates for Pharmaceutical Testing

• Main Authors: Bruno C. Sil (Author), Avnish Patel (Author), Jonathan M. Crowther (Author), David J. Moore (Author), Jonathan Hadgraft (Author), Stephen T. Hilton (Author), Majella E. Lane (Author)
• Format: Book
• Published: MDPI AG, 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In vitro permeation studies using nail clippings or nail plates are commonly used in the development of transungual formulations. However, there are ethical, safety and cost issues associated with sourcing such tissues. Herein, we describe a preliminary approach is described for the design and manuf...