Telmisartan Potentiates Insulin Secretion via Ion Channels, Independent of the AT1 Receptor and PPARγ

• Main Authors: Tao Liu (Author), Lijuan Cui (Author), Huan Xue (Author), Xiaohua Yang (Author), Mengmeng Liu (Author), Linping Zhi (Author), Huanhuan Yang (Author), Zhihong Liu (Author), Min Zhang (Author), Qing Guo (Author), Peifeng He (Author), Yunfeng Liu (Author), Yi Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Angiotensin II type 1 (AT1) receptor blockers (ARBs), as antihypertensive drugs, have drawn attention for their benefits to individuals with diabetes and prediabetes. However, the direct effects of ARBs on insulin secretion remain unclear. In this study, we aimed to investigate the insulinotropic ef...