The Role of Matrix Metalloproteinases (MMP-2 and MMP-9) in Ageing and Longevity: Focus on Sicilian Long-Living Individuals (LLIs)

• Main Authors: Patrizia Cancemi (Author), Anna Aiello (Author), Giulia Accardi (Author), Rosalia Caldarella (Author), Giuseppina Candore (Author), Calogero Caruso (Author), Marcello Ciaccio (Author), Laura Cristaldi (Author), Francesca Di Gaudio (Author), Valentina Siino (Author), Sonya Vasto (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Extracellular matrix metalloproteinases (MMPs) are a group of proteins that activate substrates by enzymatic cleavage and, on the basis of their activities, have been demonstrated to play a role in ageing. Thus, in order to gain insight into the pathophysiology of ageing and to identify new markers...